Streptomycetes are special: arcane applications

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Streptomycetes are special: arcane applications

The evolution and spread of antibiotic resistance determinants in human and animal pathogens has caused increased morbidity and mortality of infection throughout the world, with correspondingly staggering increases in cost to health-care systems (Davies and Davies, 2010). Although a proportion of this epidemic is a result of mutation, it is considered that most occurs through the acquisition of...

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An arcane cardiomyopathy

Last February, the Lancet and the New England Journal of Medicine almost simultaneously published two interesting case reports on an arcane cardiomyopathy [1, 2]. The New York Times drew attention to these papers in their Health Section as ‘A Medical Mystery Solved’. A 55-year-old man is described. He was hospitalised for severe heart failure after he had gone from doctor to doctor seeking a di...

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Streptomyces subtilisin inhibitor-like proteins are distributed widely in streptomycetes.

Streptomyces subtilisin inhibitor-like proteins were found to be distributed widely in streptomycetes by using the combination of the convenient, newly developed plate assay system and an established liquid culture assay. Almost all the strains formerly categorized as Streptoverticillium species produced proteins that exhibited inhibitory activity against both subtilisin BPN' and trypsin. N-ter...

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Isolation of thermophilic streptomycetes.

The thermophilic streptomycetes, growing in the temperature range of 55 to 65 C, have remained a little known group of microorganisms. Since their discovery in 1888 by Golbig, their physiology, metabolism, metabolic products, natural habitat, and even their morphology have remained unknown or in the realm of conjecture. It was only in the latest edition of Bergey's Manual of Determinative Bacte...

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A study of the bacteriolytic properties of streptomycetes has progressively uncovered the production by these microorganisms of a large number of different enzymes acting upon various bacterial constituents, especially on some of them located in the cell wall. Although the mechanism of the bacteriolysis is far from being completely elucidated at present, it can, however, be stated that, in two ...

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ژورنال

عنوان ژورنال: Microbial Biotechnology

سال: 2010

ISSN: 1751-7915

DOI: 10.1111/j.1751-7915.2010.00238.x